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Pyloric Stenosis

  • Pyloric Stenosis is a congenital anatomic disorder of development characterized by an inappropriate hypertrophy of the pylorus muscle resulting in an excessively narrow pyloric sphinter that prevents normal gastric emptying. The disease is typically observed in boys.
Clinical Consequences
  • Pyloric Stenosis becomes clinically apparent in neonates during the second to third week after birth and is characterized by projectile vomiting. This is due to backup of ingested food in the alimentary tract due to defective gastric motility, specifically gastric emptying. Additionally, the hypertrophied pylorus muscle can often be palpated as an firm, ovoid intra-abdominal mass.
  • Treatment is surgical and involves incision of the pylorus muscle.