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Thyroid Anaplastic Carcinoma

  • Thyroid Anaplastic Carcinoma is a type of malignant neoplasm of the thyroid gland whose cell of origin is the thyroid follicular epithelial cell.
  • Gross Appearance
    • Thyroid Anaplastic Carcinoma may be visible as a rapidly growing mass in the neck.
  • Histological Appearance
    • Neoplasms are composed of small anaplastic cells of variegated appearance in multiple architectural patterns. Neoplastic cells are highly invasive and rapidly grow past the thyroid capsule.
Clinical Consequences
  • Thyroid anaplastic carcinomas are malignant, rapidly metastasize, and consequently possess extremely poor prognoses. Clinical consequences mostly arises from local invasion into adjacent neck structures.