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Renal Tubular Acidosis

  • Renal Tubular Acidosis (RTA) refers to a group of diseases that can be inherited or acquired and are characterized by a defect in the capacity of the kidney to resorb bicarbonate (See: Renal Bicarbonate Excretion) or excrete acid (See: Renal Acid Excretion), thus resulting in metabolic acidosis. In each case, defects of tubular function are not limited to bicarbonate or acid transport and may include defects in resorption of glucose, amino acids, and phosphate yielding concomitant glucosuria, Aminoaciduria, and hypophosphatemia. Note that one subtype of RTA is termed "Fanconi Syndrome".