Hereditary Nonpolyposis Colon Cancer (HNPCC)
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- Hereditary Nonpolyposis Colon Cancer (HNPCC) refers to development of colorectal carcinoma in an individual less than 50 years old together with a defined extensive family history of colon cancer that follows an autosomal dominant pattern. HNPCC is likely not a distinct etiological condition but can arise from germline mutations in a variety of genes.