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Deprecated function: The each() function is deprecated. This message will be suppressed on further calls in book_prev() (line 775 of /home/pathwa23/public_html/modules/book/book.module).


  • An Ephelis, known commonly as a "Freckle", is a small hyperpigmented well-demarcated macule present, often in large numbers, on sun-exposed skin. Most epheli develop during childhood in susceptible light-skinned individuals. Freckles characteristically darken with sun-exposure. Histologically, epheli represent an increase in the amount of melanin pigment in the basal layer of the skin in the context of normal numbers of melanocytes.