Adenovirus
Categorization | |
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Genome: DNA Virus, dsDNA Virus | Structure: Nonenveloped Virus, Icosahedral Virus |
Overview |
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- Adenoviruses are a family of related viruses which share a common structure, pattern of infection, and result in similar clinical consequences.
Pathogenesis |
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- Adenoviruses only effectively infect epithelia and can cause disease in the respiratory epithelium, GI epithelium, and conjunctiva. In general, infection is most common in children.
Clinical Consequences |
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- Upper Respiratory Infection:
- Characterized by rhinitis, pharyngitis, and fever. Occasionally, infection can lead to pneumonia but this is rare.
- Infectious Diarrhea
- Infection of the GI system can lead to infectious diarrhea, mostly in children.
- Conjunctivitis
- Infection of the eye's conjunctiva is often a component of adenoviral URI. A more severe, solitary keratoconjunctivitis popularly known as "Pink Eye" is also possible with certain serotypes.