Rotaviruses

Categorization
Genome: RNA Virus, dsRNA Virus, Segmented Virus Structure: Nonenveloped Virus, Icosahedral Virus
Overview
  • Rotaviruses are a family of structurally-related viruses which are the most common cause of viral infectious diarrhea.
Pathogenesis
Clinical Consequences
  • Rotavirus infection usually manifests as a febrile watery diarrhea 1-2 days after inoculation. Abdominal pain and vomiting]] often occur during infection and severe cases can lead to potentially life-threatening dehydration.
Epidemiology
  • Rotaviruses are ubiquitous and most individuals are infected as infants or children. Because immunity is often life-long, rotaviral gastroenteritis is mostly observed in young age groups as adults are typicaly immune due to previous, repeated childhood infectious.