Rapidly Progressive Glomerulonephritis (RPGN)
- Rapidly Progressive Glomerulonephritis (RPGN) is a histopathological morphology of glomerulonephritis which can be caused by a wide variety of diseases. RPGN is characterized by the extremely rapid development of the signs and symptoms traditional nephritic syndrome.
- RPGN is histopathologically characterized by the presence of cellular "Crescents" within Bowman's space and is thus sometimes termed "Crescentic Glomerulonephritis". These crescents are composed of a variety of cells but include inflammatory cells
- During the course of disease they may enlarge to completely obliterate the glomerulus.
|Etiology and Pathogenesis|