Pleomorphic Adenoma

Overview
  • Pleomorphic Adenomas are thought to arise from the salivary gland myoepithelial cell and typically occur in the parotid glands. These tumors are the most common of the benign neoplasia of the salivary glands. However, although typically benign, pleomorphic adenomas can recur after excision and rarely can undergo malignant transformation.
Morphology
  • Plemorphic Adnemoas are typically well-encapsulated and demarcated lesions which, as their name suggests, display a wide variety of histomorphologies with ductal and tubular elements present within a loose mesenchymal tissue. Lesions often present as a painless, palpable mass on the line of the jaw that can reach a few centimeters in size.