Parainfluenza Virus

Categorization
Class: Paramyxoviruses
Genome: RNA Virus, Negative ssRNA Virus Structure: Enveloped Virus
Pathogenesis
  • Like all paramyxoviruses, Parainfluenza Virus initially inoculates and replicates in the upper respiratory tract. In some individuals it can spread to the lower respiratory tract, resulting in disease; however, Parainfluenza virus does not appear to disseminate viremically to distant organs.
Clinical Consequences
  • In most cases, infections remains limited to the upper respiratory tract and results in symptomology similar to the common cold such as rhinitis, pharyngitis, and coryza. However, spread to the lower respiratory tract can result in laryngotracheobronchitis or community-acquired pneumonia.