Metaplasia

Overview
  • Metaplasia refers to a reversible histological replacement of one differentiated cell type with another. Although by definition metaplasia is a reversible adaptation, it frequently precedes and may represent the initial steps of malignant transformation.
Etiologies
  • Metaplasia is frequently induced by chronic cellular injury and represents an adaptation in which a tissue replaces a sensitive cell type with one better able to resist the injury. Use the search function for specific examples.