Leukoplakia
Etiology |
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- Leukoplakia can essentially be thought of as a precancerous lesion of the oral mucosa resulting from chronic insult to the tissue. Leukoplakia might be visually confused with oral candidiasis; however the lesion of leukoplakia cannot be scrapped off. Leukoplakia also sounds similar to Hairy Leukoplakia; however, these diseases have distinct etiologies.
Morphology |
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- Gross Appearnce: Appears as a discrete whitish plaque occurring anywhere on the oral mucosa that cannot be scraped off.
- Histological Appearance: Ranges from hyperkeratosis all the way to lesions containing significant dysplasia just short of carcinoma in situ.
Incidence |
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- Tends to occur in men with a history of smoking, alcohol abuse, or some other irritant of the oral mucosa such as poorly-fitting dentures.
Clinical Consequences |
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- Frequently benign but carries the risk of developing into oral cancer.