- Hepatorenal syndrome refers to the emergence of acute renal failure in a patient with hepatic failure in the absence of overt renal pathology.
- The pathogenesis of Hepatorenal Syndrome is not well understood but is clearly precipitated by liver failure. It appears that a drop in systemic vascular resistance due to vasodilation of splanchnic organs results in reduced blood flow to the kidneys. Because there is an absence of renal pathology and renal failure is due to reduced renal blood flow, hepatorenal syndrome is classified as prerenal acute renal failure.
- Hepatorenal syndrome results in acute renal failure (see page for symptomology).