Craniopharyngioma

Overview
  • Craniopharyngiomas are neoplasms which arise either within or just above the sella turcica. Neoplastic cells are likely derived from epithelial remnants of the embryological pharynx known as Rathke's Pouch
Clinical Consequences
  • Craniopharyngiomas are typically slow-growing benign tumors and cause clinical consequences due to physical impingement on local structures
  • Increased intracranial pressure often results in Headaches, vomiting, and papilledema
  • Impingement of the optic chiasm will result in bilateral hemianopia
  • The expanding mass can often place significant pressure on the pituitary gland resulting in substantial damage to the gland
  • Damage to the anterior pituitary can result in signs and symptoms of hypopituitarism
  • Damage to the posterior pituitary can result in Diabetes Insipidus