Amniotic Fluid Embolism

Overview
  • Amniotic Fluid Emboli are a subtype of emboli caused by the release of amniotic fluid into the maternal venous circulation either via uterine veins or tears within the placenta itself. It is not precisely clear how amniotic fluid causes pathology and may be due to direct deposition or thrombotic initiation by particulate matter shed by the fetus.
Clinical Consequences
  • Although a very rare obstetric event in regnant women, amniotic fluid emboli are highly fatal and cause death in 90% of cases. Death results from a combination of ARDS and DIC.